Calling all uptown girls!

 Designer Derek Lam is opening his second Manhattan store this fall, on Madison Avenue. "This is my latest collaboration with Pritzker-prizewinning architects SANAA, whose abil-ity to create a space that is minimalist yet warm has become part of our aesthetic," Lam says of the boutique, which joins his much-celebrated Crosby Street locale. The gallery-like interior showcases Lam's luxe fur toppers, breezy blouses, and other smart separates.